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The Role of the Blood-Brain Barrier in the Pathogenesis of Senile Plaques in Alzheimer's Disease
The accumulation of beta-amyloid [Aβ] within senile plaques [SP] is characteristic of these lesions in Alzheimer's disease. The accumulation of Aβ (42), in particular, in the superior temporal [ST] cortex may result from an inability of the blood brain barrier (BBB) to regulate the trans-endoth...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189524/ https://www.ncbi.nlm.nih.gov/pubmed/25309772 http://dx.doi.org/10.1155/2014/191863 |