Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis

BACKGROUND: The maintenance of stem cell pluripotency is controlled by a core cluster of transcription factors, NANOG, OCT4 and SOX2 – genes that jointly regulate each other’s expression. The expression of some of these genes, especially of Nanog, is heterogeneous in a population of undifferentiated...

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Detalles Bibliográficos
Autores principales: Lakatos, Dora, Travis, Emily D, Pierson, Kelsey E, Vivian, Jay L, Czirok, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189679/
https://www.ncbi.nlm.nih.gov/pubmed/25267505
http://dx.doi.org/10.1186/s12918-014-0112-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189679/
https://www.ncbi.nlm.nih.gov/pubmed/25267505
http://dx.doi.org/10.1186/s12918-014-0112-4

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