Cargando…
Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: a computational analysis
BACKGROUND: The maintenance of stem cell pluripotency is controlled by a core cluster of transcription factors, NANOG, OCT4 and SOX2 – genes that jointly regulate each other’s expression. The expression of some of these genes, especially of Nanog, is heterogeneous in a population of undifferentiated...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189679/ https://www.ncbi.nlm.nih.gov/pubmed/25267505 http://dx.doi.org/10.1186/s12918-014-0112-4 |