Anti-Heparanase Aptamers as Potential Diagnostic and Therapeutic Agents for Oral Cancer

Heparanase is an endoglycosidase enzyme present in activated leucocytes, mast cells, placental tissue, neutrophils and macrophages, and is involved in tumour metastasis and tissue invasion. It presents a potential target for cancer therapies and various molecules have been developed in an attempt to...

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Detalles Bibliográficos
Autores principales: Simmons, Suzanne C., Jämsä, Hannaleena, Silva, Dilson, Cortez, Celia M., McKenzie, Edward A., Bitu, Carolina C., Salo, Sirpa, Nurmenniemi, Sini, Nyberg, Pia, Risteli, Juha, deAlmeida, Carlos E. B., Brenchley, Paul E. C., Salo, Tuula, Missailidis, Sotiris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189786/
https://www.ncbi.nlm.nih.gov/pubmed/25295847
http://dx.doi.org/10.1371/journal.pone.0096846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189786/
https://www.ncbi.nlm.nih.gov/pubmed/25295847
http://dx.doi.org/10.1371/journal.pone.0096846

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