Involvement of Tumor Macrophage HIFs in Chemotherapy Effectiveness: Mathematical Modeling of Oxygen, pH, and Glutathione

The four variables, hypoxia, acidity, high glutathione (GSH) concentration and fast reducing rate (redox) are distinct and varied characteristics of solid tumors compared to normal tissue. These parameters are among the most significant factors underlying the metabolism and physiology of solid tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Duan, Bobko, Andrey A., Gross, Amy C., Evans, Randall, Marsh, Clay B., Khramtsov, Valery V., Eubank, Timothy D., Friedman, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189793/
https://www.ncbi.nlm.nih.gov/pubmed/25295611
http://dx.doi.org/10.1371/journal.pone.0107511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189793/
https://www.ncbi.nlm.nih.gov/pubmed/25295611
http://dx.doi.org/10.1371/journal.pone.0107511

Ejemplares similares