Genome-wide determination of drug localization

A vast number of small-molecule ligands, including therapeutic drugs under development and in clinical use, elicit their effects by binding specific proteins associated with the genome. An ability to map the direct interactions of a chemical entity with chromatin genome-wide could provide new and im...

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Detalles Bibliográficos
Autores principales: Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189815/
https://www.ncbi.nlm.nih.gov/pubmed/24336317
http://dx.doi.org/10.1038/nbt.2776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189815/
https://www.ncbi.nlm.nih.gov/pubmed/24336317
http://dx.doi.org/10.1038/nbt.2776

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