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Comparison of 2 synthetically generated recombinant prions

Prion is a protein-conformation-based infectious agent causing fatal neurodegenerative diseases in humans and animals. Our previous studies revealed that in the presence of cofactors, infectious prions can be synthetically generated in vitro with bacterially expressed recombinant prion protein (PrP)...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Wang, Fei, Wang, Xinhe, Zhang, Zhihong, Xu, Yuanyuan, Yu, Guohua, Yuan, Chonggang, Ma, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189893/
https://www.ncbi.nlm.nih.gov/pubmed/24721728
http://dx.doi.org/10.4161/pri.28669