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Peroxidasin is essential for eye development in the mouse

Mutations in Peroxidasin (PXDN) cause severe inherited eye disorders in humans, such as congenital cataract, corneal opacity and developmental glaucoma. The role of peroxidasin during eye development is poorly understood. Here, we describe the first Pxdn mouse mutant which was induced by ENU (N-ethy...

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Detalles Bibliográficos
Autores principales: Yan, Xiaohe, Sabrautzki, Sibylle, Horsch, Marion, Fuchs, Helmut, Gailus-Durner, Valerie, Beckers, Johannes, Hrabě de Angelis, Martin, Graw, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189897/
https://www.ncbi.nlm.nih.gov/pubmed/24895407
http://dx.doi.org/10.1093/hmg/ddu274