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What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit

The GRIA1 locus, encoding the GluA1 (also known as GluRA or GluR1) AMPA glutamate receptor subunit, shows genome-wide association to schizophrenia. As well as extending the evidence that glutamatergic abnormalities play a key role in the disorder, this finding draws attention to the behavioural phen...

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Detalles Bibliográficos
Autores principales: Barkus, C, Sanderson, DJ, Rawlins, JNP, Walton, ME, Harrison, PJ, Bannerman, DM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189912/
https://www.ncbi.nlm.nih.gov/pubmed/25224260
http://dx.doi.org/10.1038/mp.2014.91