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Self DNA from Lymphocytes That Have Undergone Activation-Induced Cell Death Enhances Murine B Cell Proliferation and Antibody Production

Systemic lupus erythematosus (SLE) is characterized by prominent autoinflammatory tissue damage associated with impaired removal of dying cells and DNA. Self DNA-containing immune complexes are able to activate both innate and adaptive immune responses and play an important role in the maintenance a...

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Detalles Bibliográficos
Autores principales: Lu, Qing, Wang, Ji-Yang, Wang, Luman, Jiang, Xuechao, Chu, Yiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189923/
https://www.ncbi.nlm.nih.gov/pubmed/25296026
http://dx.doi.org/10.1371/journal.pone.0109095