Structure of cohesin subcomplex pinpoints direct shugoshin–Wapl antagonism in centromeric cohesion

Orderly termination of sister-chromatid cohesion during mitosis is critical for accurate chromosome segregation. During prophase, mitotic kinases phosphorylate cohesin and its protector sororin, triggering Wapl-dependent cohesin release from chromosome arms. The shugoshin (Sgo1)–PP2A complex protect...

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Detalles Bibliográficos
Autores principales: Hara, Kodai, Zheng, Ge, Qu, Qianhui, Liu, Hong, Ouyang, Zhuqing, Chen, Zhe, Tomchick, Diana R., Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190070/
https://www.ncbi.nlm.nih.gov/pubmed/25173175
http://dx.doi.org/10.1038/nsmb.2880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190070/
https://www.ncbi.nlm.nih.gov/pubmed/25173175
http://dx.doi.org/10.1038/nsmb.2880

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