Mechanochemical basis of protein degradation by a double-ring AAA+ machine

Molecular machines containing double or single AAA+ rings power energy-dependent protein degradation and other critical cellular processes, including disaggregation and remodeling of macromolecular complexes. How the mechanical activities of double-ring and single-ring AAA+ enzymes differ is unknown...

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Detalles Bibliográficos
Autores principales: Olivares, Adrian O., Nager, Andrew R., Iosefson, Ohad, Sauer, Robert T., Baker, Tania A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190165/
https://www.ncbi.nlm.nih.gov/pubmed/25195048
http://dx.doi.org/10.1038/nsmb.2885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190165/
https://www.ncbi.nlm.nih.gov/pubmed/25195048
http://dx.doi.org/10.1038/nsmb.2885

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