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Biosynthesis of Taxadiene in Saccharomyces cerevisiae : Selection of Geranylgeranyl Diphosphate Synthase Directed by a Computer-Aided Docking Strategy

Identification of efficient key enzymes in biosynthesis pathway and optimization of the fitness between functional modules and chassis are important for improving the production of target compounds. In this study, the taxadiene biosynthesis pathway was firstly constructed in yeast by transforming ts...

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Detalles Bibliográficos
Autores principales: Ding, Ming-zhu, Yan, Hui-fang, Li, Lin-feng, Zhai, Fang, Shang, Lu-qing, Yin, Zheng, Yuan, Ying-jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190181/
https://www.ncbi.nlm.nih.gov/pubmed/25295588
http://dx.doi.org/10.1371/journal.pone.0109348