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Biosynthesis of Taxadiene in Saccharomyces cerevisiae : Selection of Geranylgeranyl Diphosphate Synthase Directed by a Computer-Aided Docking Strategy
Identification of efficient key enzymes in biosynthesis pathway and optimization of the fitness between functional modules and chassis are important for improving the production of target compounds. In this study, the taxadiene biosynthesis pathway was firstly constructed in yeast by transforming ts...
Autores principales: | Ding, Ming-zhu, Yan, Hui-fang, Li, Lin-feng, Zhai, Fang, Shang, Lu-qing, Yin, Zheng, Yuan, Ying-jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190181/ https://www.ncbi.nlm.nih.gov/pubmed/25295588 http://dx.doi.org/10.1371/journal.pone.0109348 |
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