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Natural Aminoacyl tRNA Synthetase Fragment Enhances Cardiac Function after Myocardial Infarction

A naturally-occurring fragment of tyrosyl-tRNA synthetase (TyrRS) has been shown in higher eukaryotes to ‘moonlight’ as a pro-angiogenic cytokine in addition to its primary role in protein translation. Pro-angiogenic cytokines have previously been proposed to be promising therapeutic mechanisms for...

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Detalles Bibliográficos
Autores principales: McCormick, Margaret E., Rojas, Mauricio, Moser-Katz, Tyler, Tzima, Ellie, Reader, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190278/
https://www.ncbi.nlm.nih.gov/pubmed/25296172
http://dx.doi.org/10.1371/journal.pone.0109325