Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor

BACKGROUND: Natural killer (NK) cells eliminate virus-infected and tumor cells through the release of perforins and granzymes; they also produce Interferon gamma (IFN-γ) and Tumor necrosis factor alpha (TNF-α), which induce apoptosis in target cells. Many tumors express Heme oxygenase 1 (HO-1), and...

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Detalles Bibliográficos
Autores principales: Gómez-Lomelí, Paulina, Bravo-Cuellar, Alejandro, Hernández-Flores, Georgina, Jave-Suárez, Luis Felipe, Aguilar-Lemarroy, Adriana, Lerma-Díaz, José Manuel, Domínguez-Rodríguez, Jorge Ramiro, Sánchez-Reyes, Karina, Ortiz-Lazareno, Pablo Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190300/
https://www.ncbi.nlm.nih.gov/pubmed/25302050
http://dx.doi.org/10.1186/s12935-014-0100-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190300/
https://www.ncbi.nlm.nih.gov/pubmed/25302050
http://dx.doi.org/10.1186/s12935-014-0100-1

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