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Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis

BACKGROUND: The genetic cascades underpinning vertebrate early eye morphogenesis are poorly understood. One gene family essential for eye morphogenesis encodes the retinal homeobox (Rx) transcription factors. Mutations in the human retinal homeobox gene (RAX) can lead to gross morphological phenotyp...

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Detalles Bibliográficos
Autores principales: Yin, Jun, Morrissey, Maria E, Shine, Lisa, Kennedy, Ciarán, Higgins, Desmond G, Kennedy, Breandán N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190348/
https://www.ncbi.nlm.nih.gov/pubmed/25266257
http://dx.doi.org/10.1186/1471-2164-15-825