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Reduced Mucosal Associated Invariant T-Cells Are Associated with Increased Disease Severity and Pseudomonas aeruginosa Infection in Cystic Fibrosis

BACKGROUND: Primary defects in host immune responses have been hypothesised to contribute towards an inability of subjects with cystic fibrosis (CF) to effectively clear pulmonary infections. Innate T-lymphocytes provide rapid pathogen-specific responses prior to the development of classical MHC cla...

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Detalles Bibliográficos
Autores principales: Smith, Daniel J., Hill, Geoffrey R., Bell, Scott C., Reid, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190362/
https://www.ncbi.nlm.nih.gov/pubmed/25296025
http://dx.doi.org/10.1371/journal.pone.0109891