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Pioglitazone modulates the proliferation and apoptosis of vascular smooth muscle cells via peroxisome proliferators-activated receptor-gamma

BACKGROUND: PPARγ is a member of the nuclear hormone receptor superfamily. It has been considered as a mediator regulating metabolism, anti-inflammation, and pro-proliferation in the Vascular Smooth Muscle Cells (VSMCs). Thiazolidinediones (TZDs), synthetic ligands of PPARγ, have anti-proliferative...

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Detalles Bibliográficos
Autores principales: Wan, Jing, Xiao, Zhichao, Chao, Shengping, Xiong, Shixi, Gan, Xuedong, Qiu, Xuguang, Xu, Chang, Ma, Yexin, Tu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190377/
https://www.ncbi.nlm.nih.gov/pubmed/25302079
http://dx.doi.org/10.1186/1758-5996-6-101