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Inhibition of Na(+)/K(+)-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells
BACKGROUND: Glioblastoma multiforme (GBM) is very difficult to treat with conventional anti-cancer/anti-apoptotic drugs. We tested the hypothesis that inhibition of Na(+)/K(+)-ATPase causes a mixed or hybrid form of concurrent apoptosis and necrosis and therefore should enhance anti-cancer effects o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190379/ https://www.ncbi.nlm.nih.gov/pubmed/25255962 http://dx.doi.org/10.1186/1471-2407-14-716 |