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Nicotine Stimulates Nerve Growth Factor in Lung Fibroblasts through an NFκB-Dependent Mechanism

RATIONALE: Airway hyperresponsiveness (AHR) is classically found in asthma, and persistent AHR is associated with poor asthma control. Although airway smooth muscle (ASM) cells play a critical pathophysiologic role in AHR, the paracrine contributions of surrounding cells such as fibroblasts to the c...

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Detalles Bibliográficos
Autores principales: Wongtrakool, Cherry, Grooms, Kora, Bijli, Kaiser M., Crothers, Kristina, Fitzpatrick, Anne M., Hart, C. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190411/
https://www.ncbi.nlm.nih.gov/pubmed/25296021
http://dx.doi.org/10.1371/journal.pone.0109602