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Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro

BACKGROUND: Pancreatic cancer is frequently resistant to cancer therapeutics. Smoking and alcoholism are risk factors and pancreatic cancer patients often undergo nicotine replacement therapy (NRT) and treatment for alcohol dependence. Based on our report that low dose nicotine within the range of N...

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Detalles Bibliográficos
Autores principales: Banerjee, Jheelam, Al-Wadei, Hussein AN, Al-Wadei, Mohammed H, Dagnon, Koami, Schuller, Hildegard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190427/
https://www.ncbi.nlm.nih.gov/pubmed/25260978
http://dx.doi.org/10.1186/1471-2407-14-725