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Next-generation sequencing identifies equine cartilage and subchondral bone miRNAs and suggests their involvement in osteochondrosis physiopathology

BACKGROUND: MicroRNAs (miRNAs) are an abundant class of small single-stranded non-coding RNA molecules ranging from 18 to 24 nucleotides. They negatively regulate gene expression at the post-transcriptional level and play key roles in many biological processes, including skeletal development and car...

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Detalles Bibliográficos
Autores principales: Desjardin, Clémence, Vaiman, Anne, Mata, Xavier, Legendre, Rachel, Laubier, Johan, Kennedy, Sean P, Laloe, Denis, Barrey, Eric, Jacques, Claire, Cribiu, Edmond P, Schibler, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190437/
https://www.ncbi.nlm.nih.gov/pubmed/25227120
http://dx.doi.org/10.1186/1471-2164-15-798