Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury

BACKGROUND: Optic nerve damage initiates a series of early atrophic events in retinal ganglion cells (RGCs) that precede the BAX-dependent committed step of the intrinsic apoptotic program. Nuclear atrophy, including global histone deacetylation, heterochromatin formation, shrinkage and collapse of...

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Detalles Bibliográficos
Autores principales: Schmitt, Heather M, Pelzel, Heather R, Schlamp, Cassandra L, Nickells, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190472/
https://www.ncbi.nlm.nih.gov/pubmed/25261965
http://dx.doi.org/10.1186/1750-1326-9-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190472/
https://www.ncbi.nlm.nih.gov/pubmed/25261965
http://dx.doi.org/10.1186/1750-1326-9-39

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