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Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL

Genomic aberrations involving ETV6 on band 12p13 are amongst the most common chromosomal abnormalities in human leukemia. The translocation t(6;12)(q23;13) in a childhood B-cell acute lymphoblastic leukemia (ALL) cell line fuses ETV6 with the putative long non-coding RNA gene STL. Linking STL proper...

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Detalles Bibliográficos
Autores principales: Fontanari Krause, Luciana M., Japp, Anna Sophia, Krause, Alexandre, Mooster, Jana, Chopra, Martin, Müschen, Markus, Bohlander, Stefan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190505/
https://www.ncbi.nlm.nih.gov/pubmed/25298122
http://dx.doi.org/10.1038/srep06565