Encapsulated Cells Expressing a Chemotherapeutic Activating Enzyme Allow the Targeting of Subtoxic Chemotherapy and Are Safe and Efficacious: Data from Two Clinical Trials in Pancreatic Cancer

Despite progress in the treatment of pancreatic cancer, there is still a need for improved therapies. In this manuscript, we report clinical experience with a new therapy for the treatment of pancreatic cancer involving the implantation of encapsulated cells over-expressing a cytochrome P450 enzyme...

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Detalles Bibliográficos
Autores principales: Löhr, J. Matthias, Haas, Stephan L., Kröger, Jens C., Friess, Helmut M., Höft, Raimund, Goretzki, Peter E., Peschel, Christian, Schweigert, Markus, Salmons, Brian, Gunzburg, Walter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190529/
https://www.ncbi.nlm.nih.gov/pubmed/25116885
http://dx.doi.org/10.3390/pharmaceutics6030447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190529/
https://www.ncbi.nlm.nih.gov/pubmed/25116885
http://dx.doi.org/10.3390/pharmaceutics6030447

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