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Creatine kinase inhibits ADP-induced platelet aggregation

Bleeding risk with antiplatelet therapy is an increasing clinical challenge. However, the inter-individual variation in this risk is poorly understood. We assessed whether the level of plasma creatine kinase, the enzyme that utilizes ADP and phosphocreatine to rapidly regenerate ATP, may modulate bl...

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Detalles Bibliográficos
Autores principales: Horjus, D. L., Nieuwland, R., Boateng, K. B., Schaap, M. C. L., van Montfrans, G. A., Clark, J. F., Sturk, A., Brewster, L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190537/
https://www.ncbi.nlm.nih.gov/pubmed/25298190
http://dx.doi.org/10.1038/srep06551