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Phosphorylation of Large T Antigen Regulates Merkel Cell Polyomavirus Replication

Merkel Cell Polyomavirus (MCPyV) was recently discovered as a novel human polyomavirus that is associated with ~80% of Merkel Cell Carcinomas. The Large Tumor antigen (LT) is an early viral protein which has a variety of functions, including manipulation of the cell cycle and initiating viral DNA re...

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Detalles Bibliográficos
Autores principales: Diaz, Jason, Wang, Xin, Tsang, Sabrina H., Jiao, Jing, You, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190550/
https://www.ncbi.nlm.nih.gov/pubmed/25006834
http://dx.doi.org/10.3390/cancers6031464