The c-Met Inhibitor MSC2156119J Effectively Inhibits Tumor Growth in Liver Cancer Models

The mesenchymal-epithelial transition factor (c-Met) is a receptor tyrosine kinase with hepatocyte growth factor (HGF) as its only high-affinity ligand. Aberrant activation of c-Met is associated with many human malignancies, including hepatocellular carcinoma (HCC). We investigated the in vivo anti...

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Detalles Bibliográficos
Autores principales: Bladt, Friedhelm, Friese-Hamim, Manja, Ihling, Christian, Wilm, Claudia, Blaukat, Andree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190565/
https://www.ncbi.nlm.nih.gov/pubmed/25256830
http://dx.doi.org/10.3390/cancers6031736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190565/
https://www.ncbi.nlm.nih.gov/pubmed/25256830
http://dx.doi.org/10.3390/cancers6031736

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