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The c-Met Inhibitor MSC2156119J Effectively Inhibits Tumor Growth in Liver Cancer Models
The mesenchymal-epithelial transition factor (c-Met) is a receptor tyrosine kinase with hepatocyte growth factor (HGF) as its only high-affinity ligand. Aberrant activation of c-Met is associated with many human malignancies, including hepatocellular carcinoma (HCC). We investigated the in vivo anti...
Autores principales: | Bladt, Friedhelm, Friese-Hamim, Manja, Ihling, Christian, Wilm, Claudia, Blaukat, Andree |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190565/ https://www.ncbi.nlm.nih.gov/pubmed/25256830 http://dx.doi.org/10.3390/cancers6031736 |
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