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T Cell Expression of Granulocyte–Macrophage Colony-Stimulating Factor in Juvenile Arthritis Is Contingent Upon Th17 Plasticity

OBJECTIVE: Granulocyte–macrophage colony stimulating factor (GM-CSF) is a potent inflammatory mediator that is responsible for recruitment and activation of innate immune cells. Recent data from murine studies have identified Th17 cells as a key source of GM-CSF and suggest that T cell–derived GM-CS...

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Detalles Bibliográficos
Autores principales: Piper, Christopher, Pesenacker, Anne M, Bending, David, Thirugnanabalan, Balathas, Varsani, Hemlata, Wedderburn, Lucy R, Nistala, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190686/
https://www.ncbi.nlm.nih.gov/pubmed/24692225
http://dx.doi.org/10.1002/art.38647