Cargando…
T Cell Expression of Granulocyte–Macrophage Colony-Stimulating Factor in Juvenile Arthritis Is Contingent Upon Th17 Plasticity
OBJECTIVE: Granulocyte–macrophage colony stimulating factor (GM-CSF) is a potent inflammatory mediator that is responsible for recruitment and activation of innate immune cells. Recent data from murine studies have identified Th17 cells as a key source of GM-CSF and suggest that T cell–derived GM-CS...
Autores principales: | Piper, Christopher, Pesenacker, Anne M, Bending, David, Thirugnanabalan, Balathas, Varsani, Hemlata, Wedderburn, Lucy R, Nistala, Kiran |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190686/ https://www.ncbi.nlm.nih.gov/pubmed/24692225 http://dx.doi.org/10.1002/art.38647 |
Ejemplares similares
-
PReS-FINAL-2069: T cells secreting granulocyte-macrophage colony stimulating factor (GM-CSF) within the inflammed joint originate from an "EX-Th17" population
por: Nistala, K, et al.
Publicado: (2013) -
Regulatory B cell Il-10 production is diminished in juvenile dermatomyositis
por: Piper, Christopher, et al.
Publicado: (2014) -
Innate Lymphoid Cells and T Cells Contribute to the Interleukin‐17A Signature Detected in the Synovial Fluid of Patients With Juvenile Idiopathic Arthritis
por: Rosser, Elizabeth C., et al.
Publicado: (2019) -
Hypomethylation at the Regulatory T Cell–Specific Demethylated Region in CD25(hi) T Cells Is Decoupled from FOXP3 Expression at the Inflamed Site in Childhood Arthritis
por: Bending, David, et al.
Publicado: (2014) -
Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated
por: Almeida, Beverley, et al.
Publicado: (2015)