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β-arrestin2/miR-155/GSK3β regulates transition of 5′-azacytizine-induced Sca-1-positive cells to cardiomyocytes

Stem-cell antigen 1–positive (Sca-1+) cardiac stem cells (CSCs), a vital kind of CSCs in humans, promote cardiac repair in vivo and can differentiate to cardiomyocytes with 5′-azacytizine treatment in vitro. However, the underlying molecular mechanisms are unknown. β-arrestin2 is an important scaffo...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Feng, Yimin, Yan, Hui, Chen, Yangchao, Wang, Jinlan, Chua, Balvin, Stuart, Charles, Yin, Deling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190902/
https://www.ncbi.nlm.nih.gov/pubmed/24974728
http://dx.doi.org/10.1111/jcmm.12339