Embryonic viability, lipase deficiency, hypertriglyceridemia and neonatal lethality in a novel LMF1-deficient mouse model

BACKGROUND: Lipase Maturation Factor 1 (LMF1) is an ER-chaperone involved in the post-translational maturation and catalytic activation of vascular lipases including lipoprotein lipase (LPL), hepatic lipase (HL) and endothelial lipase (EL). Mutations in LMF1 are associated with lipase deficiency and...

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Detalles Bibliográficos
Autores principales: Ehrhardt, Nicole, Bedoya, Candy, Péterfy, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190935/
https://www.ncbi.nlm.nih.gov/pubmed/25302068
http://dx.doi.org/10.1186/1743-7075-11-37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190935/
https://www.ncbi.nlm.nih.gov/pubmed/25302068
http://dx.doi.org/10.1186/1743-7075-11-37

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