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Urocortin 3 activates AMPK and AKT pathways and enhances glucose disposal in rat skeletal muscle

Insulin resistance (IR) in skeletal muscle is an important component of both type 2 diabetes and the syndrome of sarcopaenic obesity, for which there are no effective therapies. Urocortins (UCNs) are not only well established as neuropeptides but also have their roles in metabolism in peripheral tis...

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Detalles Bibliográficos
Autores principales: Roustit, Manon M, Vaughan, Joan M, Jamieson, Pauline M, Cleasby, Mark E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191181/
https://www.ncbi.nlm.nih.gov/pubmed/25122003
http://dx.doi.org/10.1530/JOE-14-0181