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A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions
Identification of three-dimensional (3D) interactions between regulatory elements across the genome is crucial to unravel the complex regulatory machinery that orchestrates proliferation and differentiation of cells. ChIA-PET is a novel method to identify such interactions, where physical contacts b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191384/ https://www.ncbi.nlm.nih.gov/pubmed/25114054 http://dx.doi.org/10.1093/nar/gku738 |