Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling

MEF2 plays a profound role in the regulation of transcription in cardiac and skeletal muscle lineages. To define the overlapping and unique MEF2A genomic targets, we utilized ChIP-exo analysis of cardiomyocytes and skeletal myoblasts. Of the 2783 and 1648 MEF2A binding peaks in skeletal myoblasts an...

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Detalles Bibliográficos
Autores principales: Wales, Stephanie, Hashemi, Sara, Blais, Alexandre, McDermott, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191398/
https://www.ncbi.nlm.nih.gov/pubmed/25217591
http://dx.doi.org/10.1093/nar/gku813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191398/
https://www.ncbi.nlm.nih.gov/pubmed/25217591
http://dx.doi.org/10.1093/nar/gku813

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