Cargando…

BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle

Non-homologous end-joining (NHEJ) and homologous recombination (HR) are the two prominent pathways responsible for the repair of DNA double-strand breaks (DSBs). NHEJ is not restricted to a cell-cycle stage, whereas HR is active primarily in the S/G2 phases suggesting there are cell cycle-specific m...

Descripción completa

Detalles Bibliográficos
Autores principales: Davis, Anthony J., Chi, Linfeng, So, Sairei, Lee, Kyung-Jong, Mori, Eiichiro, Fattah, Kazi, Yang, Jun, Chen, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191403/
https://www.ncbi.nlm.nih.gov/pubmed/25223785
http://dx.doi.org/10.1093/nar/gku824