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AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis

DNA methylation is a primary epigenetic modification regulating gene expression and chromatin structure in many eukaryotes. Plants have a unique DNA demethylation system in that 5-methylcytosine (5mC) is directly removed by DNA demethylases, such as DME/ROS1 family proteins, but little is known abou...

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Detalles Bibliográficos
Autores principales: Lee, Jiyoon, Jang, Hosung, Shin, Hosub, Choi, Woo Lee, Mok, Young Geun, Huh, Jin Hoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191409/
https://www.ncbi.nlm.nih.gov/pubmed/25228464
http://dx.doi.org/10.1093/nar/gku834