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What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems

Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate selection in viral infection, cell-cycle control and d...

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Detalles Bibliográficos
Autores principales: Bhogale, Prasanna M., Sorg, Robin A., Veening, Jan-Willem, Berg, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191413/
https://www.ncbi.nlm.nih.gov/pubmed/25245949
http://dx.doi.org/10.1093/nar/gku839