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Simultaneous binding to the tracking strand, displaced strand and the duplex of a DNA fork enhances unwinding by Dda helicase

Interactions between helicases and the tracking strand of a DNA substrate are well-characterized; however, the role of the displaced strand is a less understood characteristic of DNA unwinding. Dda helicase exhibited greater processivity when unwinding a DNA fork compared to a ss/ds DNA junction sub...

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Detalles Bibliográficos
Autores principales: Aarattuthodiyil, Suja, Byrd, Alicia K., Raney, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191417/
https://www.ncbi.nlm.nih.gov/pubmed/25249618
http://dx.doi.org/10.1093/nar/gku845