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Triple helical DNA in a duplex context and base pair opening

It is fundamental to explore in atomic detail the behavior of DNA triple helices as a means to understand the role they might play in vivo and to better engineer their use in genetic technologies, such as antigene therapy. To this aim we have performed atomistic simulations of a purine-rich antipara...

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Detalles Bibliográficos
Autores principales: Esguerra, Mauricio, Nilsson, Lennart, Villa, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191418/
https://www.ncbi.nlm.nih.gov/pubmed/25228466
http://dx.doi.org/10.1093/nar/gku848