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Triple helical DNA in a duplex context and base pair opening
It is fundamental to explore in atomic detail the behavior of DNA triple helices as a means to understand the role they might play in vivo and to better engineer their use in genetic technologies, such as antigene therapy. To this aim we have performed atomistic simulations of a purine-rich antipara...
Autores principales: | Esguerra, Mauricio, Nilsson, Lennart, Villa, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191418/ https://www.ncbi.nlm.nih.gov/pubmed/25228466 http://dx.doi.org/10.1093/nar/gku848 |
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