Design and characterization of structured protein linkers with differing flexibilities

Engineered fusion proteins containing two or more functional polypeptides joined by a peptide or protein linker are important for many fields of biological research. The separation distance between functional units can impact epitope access and the ability to bind with avidity; thus the availability...

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Detalles Bibliográficos
Autores principales: Klein, Joshua S., Jiang, Siduo, Galimidi, Rachel P., Keeffe, Jennifer R., Bjorkman, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Creativity Engenders Next-Generation Antibody Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191447/
https://www.ncbi.nlm.nih.gov/pubmed/25301959
http://dx.doi.org/10.1093/protein/gzu043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191447/
https://www.ncbi.nlm.nih.gov/pubmed/25301959
http://dx.doi.org/10.1093/protein/gzu043

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