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Perturbation of Long-Range Water Dynamics as the Mechanism for the Antifreeze Activity of Antifreeze Glycoprotein

[Image: see text] Very little is known about the mechanism of antifreeze action of antifreeze glycoproteins (AFGPs) present in Antarctic teleost fish. Recent NMR and CD studies assisted with total synthesis of synthetic AFGP variants have provided insight into the structure of short AFGP glycopeptid...

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Detalles Bibliográficos
Autores principales: Mallajosyula, Sairam S., Vanommeslaeghe, Kenno, MacKerell, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191590/
https://www.ncbi.nlm.nih.gov/pubmed/25137353
http://dx.doi.org/10.1021/jp508128d