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Exploring the miRNA Regulatory Network Using Evolutionary Correlations

Post-transcriptional regulation by miRNAs is a widespread and highly conserved phenomenon in metazoans, with several hundreds to thousands of conserved binding sites for each miRNA, and up to two thirds of all genes under miRNA regulation. At the same time, the effect of miRNA regulation on mRNA and...

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Detalles Bibliográficos
Autores principales: Obermayer, Benedikt, Levine, Erel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191876/
https://www.ncbi.nlm.nih.gov/pubmed/25299225
http://dx.doi.org/10.1371/journal.pcbi.1003860