Cargando…

Disruption of SUMO-Specific Protease 2 Induces Mitochondria Mediated Neurodegeneration

Post-translational modification of proteins by small ubiquitin-related modifier (SUMO) is reversible and highly evolutionarily conserved from yeasts to humans. Unlike ubiquitination with a well-established role in protein degradation, sumoylation may alter protein function, activity, stability and s...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Jiang, Yu, H.-M. Ivy, Chiu, Shang-Yi, Mirando, Anthony J., Maruyama, Eri O., Cheng, Jr-Gang, Hsu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191884/
https://www.ncbi.nlm.nih.gov/pubmed/25299344
http://dx.doi.org/10.1371/journal.pgen.1004579