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Disruption of SUMO-Specific Protease 2 Induces Mitochondria Mediated Neurodegeneration

Post-translational modification of proteins by small ubiquitin-related modifier (SUMO) is reversible and highly evolutionarily conserved from yeasts to humans. Unlike ubiquitination with a well-established role in protein degradation, sumoylation may alter protein function, activity, stability and s...

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Detalles Bibliográficos
Autores principales:	Fu, Jiang, Yu, H.-M. Ivy, Chiu, Shang-Yi, Mirando, Anthony J., Maruyama, Eri O., Cheng, Jr-Gang, Hsu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191884/ https://www.ncbi.nlm.nih.gov/pubmed/25299344 http://dx.doi.org/10.1371/journal.pgen.1004579

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