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Sensors at Centrosomes Reveal Determinants of Local Separase Activity

Separase is best known for its function in sister chromatid separation at the metaphase-anaphase transition. It also has a role in centriole disengagement in late mitosis/G1. To gain insight into the activity of separase at centrosomes, we developed two separase activity sensors: mCherry-Scc1((142-4...

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Detalles Bibliográficos
Autores principales: Agircan, Fikret Gurkan, Schiebel, Elmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191886/
https://www.ncbi.nlm.nih.gov/pubmed/25299182
http://dx.doi.org/10.1371/journal.pgen.1004672