Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling

Folding of the chromosomal fibre in interphase nuclei is an important element in the regulation of gene expression. For instance, physical contacts between promoters and enhancers are a key element in cell-type–specific transcription. We know remarkably little about the principles that control chrom...

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Detalles Bibliográficos
Autores principales: Tark-Dame, Mariliis, Jerabek, Hansjoerg, Manders, Erik M. M., Heermann, Dieter W., van Driel, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191888/
https://www.ncbi.nlm.nih.gov/pubmed/25299688
http://dx.doi.org/10.1371/journal.pcbi.1003877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191888/
https://www.ncbi.nlm.nih.gov/pubmed/25299688
http://dx.doi.org/10.1371/journal.pcbi.1003877

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